HEMGN_MOUSE   Q9ERZ0


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UniProt:Q9ERZ0

Recommended name:Hemogen

EC number:

Alternative names:(Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR)

Cleaved into:

GeneID:93966

Gene names  (primary ):Hemgn

Gene names  (synonym ):Ndr

Gene names  (ORF ):

Length:503

Mass:55043

Sequence:MDMGKGRPRLKLPQMPEAHPQKSCAPDIIGSWSLRNREQLRKRKAEAQGRQTSQWLLGEQKKRKYQRTGKGNKRGRKRQGNVEQKAEPWSQTERERVQEVLVSAEEETEHPGNSATEALPLVPSPTKAVPADQCSEAHQESIQCQERAIQNHSQTHLSPTTCQGIAVLQHSPKMCQDMAEPEVFSPNMCQETAVPQTYPPKALEEMAAAEPLSPKMCQETTVSPNHSSKVPQDMAGPEALSPNMCQEPTVPQEHTLKMCHDVARPEVLSPKTHQEMAVPKAFPCVTPGDAAGLEGCAPKALPQSDVAEGCPLDTTPTSVTPEQTTSDPDLGMAVTEGFFSEARECTVSEGVSTKTHQEAVEPEFISHETYKEFTVPIVSSQKTIQESPEPEQYSPETCQPIPGPENYSLETCHEMSGPEDLSIKTCQDREEPKHSLPEGAQKVGGAQGQDADAQDSENAGAFSQDFTEMEEENKADQDPEAPASPQGSQETCPENGIYSSALF

Tissue specificity:Expressed in hematopoietic precursor cells. Highly expressed in bone marrow, the red pulp of the spleen and round spermatids. Weakly expressed in peripheral blood cells. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837}.

Induction:

Developmental stage:Expressed at 8.5 dpc in the blood islands of the yolk sac and in the circulating primitive blood cells. Expressed in the circulating blood cells at 9.5 dpc and 10.5 dpc. Detected in the developing hepatic primordia at 10.5 dpc. From 11.5 dpc to 14.5 dpc, exclusively expressed in the fetal liver. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837}.

Protein families:


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