CAD22_MOUSE Q9WTP5
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UniProt:Q9WTP5
Recommended name：Cadherin-22
EC number：
Alternative names：(Pituitary and brain cadherin) (PB-cadherin)
Cleaved into：
GeneID：104010
Gene names (primary )：Cdh22
Gene names (synonym )：
Gene names (ORF )：
Length：813
Mass：87953
Sequence：MRPRPEGALRAGAALSPVLLFLLLLPLLGHLWAASTPAPSSLSPGAQEDNQLGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGTIKYTISGEGAGTIFLIDELTGDIHATERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLREESGSGGDAFKVTTDSDTQEAIIVVQKHLDFESQQVHTVVLEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRDSDLEQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIEDNTAAVHTQHVGFNRQEQDVFLLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLALLILTLRRHHKSHLSSDVDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDPGGGAASPPQAASSSERHSLPRGPSSPEPDFSVFRDFISRKVALADADLSVPPYDAFQTYAFEGAGSPAASLSSLHSGSTGSEQDFAFLRAWGPRFRPLAALYAGHRGDDEAPAS
Tissue specificity：Predominantly expressed in brain. Abundant in olfactory bulb, cerebrum, and cerebellum, less in pons, medulla, and spinal cord. Low expression in heart. No expression in lung, liver, spleen, kidney, testis, stomach, intestine, colon, and placenta.
Induction：Down-regulated by thyroid hormone.
Developmental stage：Expressed at 9.5 dpc onwards. At 10.5 dpc, in brain (telencephalic vesicles and isthmus), spinal cord and limb buds (in the zone of polarizing activity). At 14.5 dpc, in olfactory bulb and cerebellum. {ECO:0000269|PubMed:10398531}.
Protein families：