ANKR2_MOUSE Q9WV06
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UniProt:Q9WV06
Recommended name:Ankyrin repeat domain-containing protein 2
EC number:
Alternative names:(Skeletal muscle ankyrin repeat protein) (mArpp)
Cleaved into:
GeneID:56642
Gene names (primary ):Ankrd2
Gene names (synonym ):Arpp
Gene names (ORF ):
Length:328
Mass:36707
Sequence:MEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ
Tissue specificity:Expressed by myoblasts (at protein level). Expressed in skeletal and cardiac muscles. {ECO:0000269|PubMed:10873377}.
Induction:Up-regulated in response to mechanical stretch of skeletal muscle (hypertrophy mechanically-induced). {ECO:0000269|PubMed:10873377}.
Developmental stage:Expressed at 9.5 dpc, with a pattern of expression that shows restricted localization to the myotome of somites. By 13.5 dpc, expression is observed within intercostal and back muscles. At 14.5 dpc and 15.5 dpc, expression is observed in tail myotomal muscles, and in intervertebral and back muscles. Hybridization was also detected within limb muscles. This pattern of expression was maintained at least up until 17.5 dpc. No localization within the heart. {ECO:0000269|PubMed:10873377}.
Protein families: