MMP24_MOUSE Q9R0S2
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UniProt:Q9R0S2
Recommended name：Matrix metalloproteinase-24
EC number：EC 3.4.24.-
Alternative names：(MMP-24) (Matrix metalloproteinase-21) (MMP-21) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP)
Cleaved into：Processed matrix metalloproteinase-24
GeneID：17391
Gene names (primary )：Mmp24
Gene names (synonym )：Mmp21 Mt5mmp
Gene names (ORF )：
Length：618
Mass：70460
Sequence：MPRSRGGRAAPGQASRWSGWRAPGRLLPLLPALCCLAAAAGAGKPAGADAPFAGQNWLKSYGYLLPYESRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERHPRPPRPPLGDRPSTPGAKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCKQKEVERRKERRLPQDDVDIMVTIDDVPGSVNAVAVVVPCTLSLCLLVLLYTIFQFKNKAGPQPVTYYKRPVQEWV
Tissue specificity：Mainly expressed in neuronal cells of both central and peripheral nervous systems. Expressed by CGRP-containing peptidergic nociceptors in dorsal root ganglia (PubMed:19805319). Expressed in adult neural stem cell and ependymocytes (PubMed:24952463). Expressed at low level in testis. {ECO:0000269|PubMed:11714638, ECO:0000269|PubMed:19805319, ECO:0000269|PubMed:24952463}.
Induction：
Developmental stage：Expressed at day 11 until day 15, before dropping around day 17 before birth. Expressed in the cerebrum in embryos, but it declines after birth, while expression in the cerebellum starts to increase postnatally and continues thereafter. {ECO:0000269|PubMed:11714638}.
Protein families：Peptidase M10A family