EOGT_MOUSE Q8BYW9
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UniProt:Q8BYW9
Recommended name:EGF domain-specific O-linked N-acetylglucosamine transferase
EC number:EC 2.4.1.255
Alternative names:(Extracellular O-linked N-acetylglucosamine transferase)
Cleaved into:
GeneID:101351
Gene names (primary ):Eogt
Gene names (synonym ):Aer61 Eogt1
Gene names (ORF ):
Length:527
Mass:61446
Sequence:MLMLLVFGVLLHEVPLSGQDKAHSEADDAPGKALYDYSSLRLPAEHIPFFLHNNRHVASVCREDSHCPYKKHLENLNYCWGYEKSCAPEFRFGSPVCSYVDLGWTDTLESAQDMFWRQADFGYARERLGEIRTICQPERASDSSLVCSRYLQYCRATGLYLDLRNIKRNHDRFKEDFLQGGEIGGYCKLDSHALVSEGQRKSPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHVNNSFSTDVYIVMWDTSTYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNITQEGPKDGKVRVTILARSTEYRKILNQDELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIHYITWRKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWPFKKKHDEL
Tissue specificity:Widely expressed. Expressed in brain, heart, kidney, lung, skeletal muscles and thymus. Highest expression is observed in lung and the lowest in skeletal muscles. {ECO:0000269|PubMed:22310717}.
Induction:
Developmental stage:Expressed at embryonic day (E) 10.5 in the growing edge of the limb buds. At 11.5 dpc, enriched in the apical ectodermal ridge of the limbs. By 12.5 dpc, expression assumes a digit-condensation pattern in the 4 limbs. {ECO:0000269|PubMed:23522784}.
Protein families:Glycosyltransferase 61 family