MBOA5_MOUSE Q91V01
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UniProt:Q91V01
Recommended name：Lysophospholipid acyltransferase 5
EC number：EC 2.3.1.-
Alternative names：(LPLAT 5) (1-acylglycerophosphocholine O-acyltransferase) (1-acylglycerophosphoethanolamine O-acyltransferase) (1-acylglycerophosphoserine O-acyltransferase) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5)
Cleaved into：
GeneID：14792
Gene names (primary )：Lpcat3
Gene names (synonym )：Grcc3f Mboat5 Oact5
Gene names (ORF )：
Length：487
Mass：56147
Sequence：MASTADGDMGETLEQMRGLWPGVEDLSLNKLATSLGASEQALRLIFSIFLGYPLALFYRHYLFYKDSYLIHLFHTFTGLSIAYFNFGHQFYHSLLCVVLQFLILRLMGRTVTAVITTLCFQMAYLLAGYYYTATGDYDIKWTMPHCVLTLKLIGLCIDYYDGGKDGNSLTSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVRGQLTDIPGKMPNSTIPALKRLSLGLVYLVGYTLLSPHITDDYLLTEDYDNRPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILSGLGFNGFDENGTVRWDACANMKVWLFETTPRFNGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLICFQMEFLIVIVEKQVSSLIRDSPALSSLASITALQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYRSIYFLGHVFFLSLLFILPYIHKAMVPRKEKLKKRE
Tissue specificity：Detected ubiquitously, with high expression levels in small intestine, brown adipose tissue, liver, kidney and testis (PubMed:18287005, PubMed:28846071, PubMed:25898003, PubMed:25806685, PubMed:24206663). Expressed in liver and both proximal and distal small intestine (at protein level) (PubMed:25898003). Expressed in peritoneal macrophages (PubMed:24206663). {ECO:0000269|PubMed:18287005, ECO:0000269|PubMed:24206663, ECO:0000269|PubMed:25806685, ECO:0000269|PubMed:25898003, ECO:0000269|PubMed:28846071}.
Induction：Up-regulated in response to liver X receptor/NR1H3 or NR1H2 agonist GW3965 (PubMed:28846071, PubMed:25898003, PubMed:25806685, PubMed:24206663). Up-regulated in peritoneal macrophages upon exposure to 22(R)-hydroxycholesterol (PubMed:24206663). {ECO:0000269|PubMed:24206663, ECO:0000269|PubMed:25806685, ECO:0000269|PubMed:25898003, ECO:0000269|PubMed:28846071}.
Developmental stage：Expressed at late embryonic stages between 18.5 and 19.5 dpc in intestine and liver. {ECO:0000269|PubMed:25898003}.
Protein families：Membrane-bound acyltransferase family