RGMC_MOUSE   Q7TQ32


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UniProt:Q7TQ32

Recommended name:Hemojuvelin

EC number:

Alternative names:(Hemochromatosis type 2 protein homolog) (Hemojuvelin BMP coreceptor) (RGM domain family member C)

Cleaved into:

GeneID:69585

Gene names  (primary ):Hjv

Gene names  (synonym ):Hfe2 Rgmc

Gene names  (ORF ):

Length:420

Mass:44848

Sequence:MGQSPSPRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSSTLSLRGGGSPDTPRGGGRGGLASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRAPGFLHCASFGDPHVRSFHNQFHTCRVQGAWPLLDNDFLFVQATSSPVSSGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSINGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIIRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQTALDDARIFLTDLENLHLFPSDAGPPLSPAICLVPLLSALFVLWLCFSK

Tissue specificity:Muscle cell lineage. {ECO:0000269|PubMed:14678836}.

Induction:

Developmental stage:Expressed at low levels in somite derived structures. In the developing eye, marked the ocular musculature. Expressed in all differentiating muscles of the limb and the body wall, but not in migrating muscle precursor cells. Not detected in the nervous system, either at 9.5 dpc or at any stage later during development. {ECO:0000269|PubMed:14678836}.

Protein families:Repulsive guidance molecule (RGM) family


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