RGMC_MOUSE Q7TQ32
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UniProt:Q7TQ32
Recommended name:Hemojuvelin
EC number:
Alternative names:(Hemochromatosis type 2 protein homolog) (Hemojuvelin BMP coreceptor) (RGM domain family member C)
Cleaved into:
GeneID:69585
Gene names (primary ):Hjv
Gene names (synonym ):Hfe2 Rgmc
Gene names (ORF ):
Length:420
Mass:44848
Sequence:MGQSPSPRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSSTLSLRGGGSPDTPRGGGRGGLASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRAPGFLHCASFGDPHVRSFHNQFHTCRVQGAWPLLDNDFLFVQATSSPVSSGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSINGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIIRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQTALDDARIFLTDLENLHLFPSDAGPPLSPAICLVPLLSALFVLWLCFSK
Tissue specificity:Muscle cell lineage. {ECO:0000269|PubMed:14678836}.
Induction:
Developmental stage:Expressed at low levels in somite derived structures. In the developing eye, marked the ocular musculature. Expressed in all differentiating muscles of the limb and the body wall, but not in migrating muscle precursor cells. Not detected in the nervous system, either at 9.5 dpc or at any stage later during development. {ECO:0000269|PubMed:14678836}.
Protein families:Repulsive guidance molecule (RGM) family