PISD_MOUSE Q8BSF4
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UniProt:Q8BSF4
Recommended name:Phosphatidylserine decarboxylase proenzyme, mitochondrial
EC number:EC 4.1.1.65
Alternative names:
Cleaved into:Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain
GeneID:320951
Gene names (primary ):Pisd
Gene names (synonym ):
Gene names (ORF ):
Length:406
Mass:45927
Sequence:MAASGGRACVRSLRGGVLWRSSPCHYESTATRHFLGTLQKLPLQAGVRNFHTAPVRSLFLLRPVPILLATGGGYAGYRQYEKYRERKLEKLGLEIPPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRANTEDLPFPPASSSDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRYSKGSYNDLSFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFGEALGSL
Tissue specificity:Widely expressed, with highest levels in testis, including Sertoli cells, followed by liver. {ECO:0000269|PubMed:16192276}.
Induction:
Developmental stage:Expressed during development in tissues rich in mitochondria, such as heart. In liver, low expression level observed in embryos and newborn animals increases 10-fold in adult. {ECO:0000269|PubMed:16192276}.
Protein families:Phosphatidylserine decarboxylase family, PSD-B subfamily, Eukaryotic type I sub-subfamily