PR2C3_MOUSE P04768
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UniProt:P04768
Recommended name:Prolactin-2C3
EC number:
Alternative names:(Mitogen-regulated protein 2) (Mitogen-regulated protein 3) (Prolactin-2C4) (Proliferin-2) (Proliferin-3)
Cleaved into:
GeneID:18812
Gene names (primary ):Prl2c3
Gene names (synonym ):Mrp2 Mrp3 Mrpplf3 Plf2 Plf3 Prl2c4
Gene names (ORF ):
Length:224
Mass:25338
Sequence:MLPSSIQPCSWILLLLLVNSSLLWKNVASFPMCAMRNGRCFMSFEDTFELAGSLSHNISIEVSELFNEFEKHYSNVSGLRDKSPMRCNTSFLPTPENKEQARLTHYAALLKSGAMILDAWESPLDDLVSELSTIKNVPDIIISKATDIKKKINAVRNGVNALMSTMLQNGDEEKKNPAWFLQSDNEDARIHSLYGMISCLDNDFKKVDIYLNVLKCYMLKIDNC
Tissue specificity:Expressed in placenta and hair follicles, with highest expression levels detected in the outer root sheath and no expression detected in bulb (PubMed:11316781). Expressed in placenta, skin wounds, keratinocytes and weakly in embryonic fibroblasts (PubMed:10537154, PubMed:11316781, PubMed:16876275). Expressed in brain, cerebellum and in Neuro-2a cell line (PubMed:16876275). Not detected in liver, kidney, ovary, pituitary gland and brain (PubMed:3859868). {ECO:0000269|PubMed:10537154, ECO:0000269|PubMed:11316781, ECO:0000269|PubMed:16876275, ECO:0000269|PubMed:3859868}.
Induction:
Developmental stage:Expressed during hair follicle morphogenesis, with highest expression levels detected at late anagen stage of the hair follicle cycle (PubMed:11316781). Expressed in developing brain from embryo to adult (PubMed:16876275). In placenta, detected at 8 dpc, peaks at 10 dpc and declines thereafter (PubMed:10537154). {ECO:0000269|PubMed:10537154, ECO:0000269|PubMed:11316781, ECO:0000269|PubMed:16876275}.
Protein families:Somatotropin/prolactin family