MAD3_MOUSE   Q80US8


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UniProt:Q80US8

Recommended name:Max dimerization protein 3

EC number:

Alternative names:(Max dimerizer 3) (Max-associated protein 3)

Cleaved into:

GeneID:17121

Gene names  (primary ):Mxd3

Gene names  (synonym ):Mad3

Gene names  (ORF ):

Length:206

Mass:23635

Sequence:MEPVASNIQVLLQAAEFLERREREAEHGYASLCPHHSPGTVCRRRKPPLQAPGALNSGRSVHNELEKRRRAQLKRCLEQLRQQMPLGVDCTRYTTLSLLRRARVHIQKLEEQEQQARRLKEKLRSKQQSLQQQLEQLQGLPGARERERLRADSLDSSGLSSERSDSDQEDLEVDVESLVFGTETELLQSFSAGREHSYSHSTCAWL

Tissue specificity:Expressed only in the proliferating areas of the testis and thymus. {ECO:0000269|PubMed:11154258}.

Induction:

Developmental stage:Expressed during neural and epidermal differentiation. Expression restricted to proliferating cells prior to differentiation. Specifically expressed in the S phase of the cell cycle in neuronal progenitor cells. In the developing embryo, detected from 9.5 to 12.5 dpc especially in the ventricular zone of the neuroepithelia, in the progression zone of the limb buds and in the aortic arches and liver. In the spinal cord at embryonic days 10.5, 11.5 and 12.5 dpc, expressed in the cells at the perimeter of the ventricular zone. In the developing epidermis, expressed only in the uppermost differentiated cell layers underneath the stratum corneum. {ECO:0000269|PubMed:11154258, ECO:0000269|PubMed:8521822}.

Protein families:


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