RSPO3_MOUSE Q2TJ95
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UniProt:Q2TJ95
Recommended name:R-spondin-3
EC number:
Alternative names:(Cabriolet) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Roof plate-specific spondin-3)
Cleaved into:
GeneID:72780
Gene names (primary ):Rspo3
Gene names (synonym ):
Gene names (ORF ):
Length:277
Mass:31454
Sequence:MHLRLISCFFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPRLFFVLERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKVDCDTCFNKNFCTKCKSGFYLHLGKCLDSCPEGLEANNHTMECVSIVHCEASEWSPWSPCMKKGKTCGFKRGTETRVRDILQHPSAKGNLCPPTSETRTCIVQRKKCSKGERGKKGRERKRKKLNKEERKETSSSSDSKGLESSIETPDQQENKERQQQQKRRARDKQQKSVSVSTVH
Tissue specificity:Highly expressed in endothelial cells (PubMed:26766444). {ECO:0000269|PubMed:26766444}.
Induction:
Developmental stage:Expressed from day 7.5 in the primitive streak. At day 9.5, it is expressed in various neural and mesodermal derivatives, mainly along dorsal neural tube, diencephalon, somites and tailbud mesoderm. Strongly expressed in limb buds, particularly in the morphogenetically active region such as the apical ectodermal ridge (AER). {ECO:0000269|PubMed:15469841}.
Protein families:R-spondin family