DPPA4_MOUSE Q8CCG4
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UniProt:Q8CCG4
Recommended name:Developmental pluripotency-associated protein 4
EC number:
Alternative names:(Embryonic stem cell-associated transcript 15-1 protein) (ECAT15-1)
Cleaved into:
GeneID:73693
Gene names (primary ):Dppa4
Gene names (synonym ):
Gene names (ORF ):
Length:296
Mass:32699
Sequence:METAGDKKWSAEEPKEEVELQMSSQPSTAPAKAKATGKKQKKSETDNGCKPKEGKPQDTETPGQTRRKVPIPPIPEYLPPVNLIHRDVLRAWCQKKRVSSKGQKLDAYKRLLARAFPEQMLELRNVPDSAKDARLKTAHKKMKTEPGEESEVTVPLEMVPVPEEQIPALIDPPMLYEEVSTTVVTTPATEAVLASWARIASNAKKYEAVPADASSSSEVKGEMWCVVHGTSLPGNSRGWVRLQFHAGQAWVPDKKGKAIALFLLPACTFPPPHLEDNMLCPKCVHKNKILTKSLEG
Tissue specificity:Expressed in pluripotent embryonic cells, but not in differentiated somatic tissues. {ECO:0000269|PubMed:12620990, ECO:0000269|PubMed:17855347, ECO:0000269|PubMed:21896782}.
Induction:
Developmental stage:Expressed in 4-cell embryo, morula and blastocyst. At 7.5 dpc, detected in the epiblast. At 10.0 dpc, expressed in the primordial germ cells and at 12.0 dpc in the embryonic gonads. At 14.5 dpc, expression is restricted to testis. 6 days after birth, still detected in primitive type A spermatogonia. Expressed in undifferentiated embryonic stem cells, but expression decreases upon differentiation (at protein level). {ECO:0000269|PubMed:12620990, ECO:0000269|PubMed:17855347, ECO:0000269|PubMed:21896782}.
Protein families: