HES6_MOUSE   Q9JHE6


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UniProt:Q9JHE6

Recommended name:Transcription cofactor HES-6

EC number:

Alternative names:(Hairy and enhancer of split 6)

Cleaved into:

GeneID:55927

Gene names  (primary ):Hes6

Gene names  (synonym ):

Gene names  (ORF ):

Length:224

Mass:24454

Sequence:MAPSQAPSRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELRLLLAGTEVQAKLENAEVLELTVRRVQGALRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLNHLLESMPLREGSSFQDLLGDSLAGLPGGSGRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVSTSLGSLTAARRAQSVWRPW

Tissue specificity:Expressed in both undifferentiated and differentiated cells. High levels of expression are observed in several embryonic tissues including the nervous system, muscle and thymus. In the nervous system, initially expressed in the closing neural tube, then in the spinal cord, cranial and dorsal root ganglia, and brain neuroepithelium. Also expressed in epithelial cells of the embryonic respiratory, urinary and digestive systems. In the limb buds, expressed in skeletal muscle and presumptive tendons. {ECO:0000269|PubMed:10906477, ECO:0000269|PubMed:11044617}.

Induction:

Developmental stage:Expressed in both embryo and adult. Expression in the embryo is detected from 8.5 dpc. In the retina, expressed at high levels at postnatal 0 dpc. Expression in brain and retina decreases postnatally but still detectable in adult. {ECO:0000269|PubMed:10851137}.

Protein families:


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