RING1_MOUSE   O35730


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UniProt:O35730

Recommended name:E3 ubiquitin-protein ligase RING1

EC number:EC 2.3.2.27

Alternative names:(Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Transcription repressor Ring1A)

Cleaved into:

GeneID:19763

Gene names  (primary ):Ring1

Gene names  (synonym ):Ring1A Rnf1

Gene names  (ORF ):

Length:406

Mass:42631

Sequence:MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPMPGSDQTATMSGGEGEPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGAGAGASSVGTGGGAAGGACGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQETTEPGGPGGGASDTGGPDGGGGERGVAGGGEGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK

Tissue specificity:

Induction:

Developmental stage:Expressed in cells of the central nervous system (CNS) from 8.5 to 11.5 dpc. Expressed in the hindbrain (in the rhombomere boundaries) at 10.5 dpc. Expressed in CNS (ventricular zone and spinal cord), peripheral nervous system (PNS, sensory cranial and spinal ganglia), olfactory and tongue epithelia at 13.5 dpc. Expressed in CNS, thymus, various epithelial cell types including the olfactory, tooth and tongue epithelia at 15.5 dpc. {ECO:0000269|PubMed:9312051}.

Protein families:


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