PRKX_MOUSE   Q922R0


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UniProt:Q922R0

Recommended name:cAMP-dependent protein kinase catalytic subunit PRKX

EC number:EC 2.7.11.1

Alternative names:(PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (PKA-related protein kinase)

Cleaved into:

GeneID:19108

Gene names  (primary ):Prkx

Gene names  (synonym ):Pkare

Gene names  (ORF ):

Length:355

Mass:40467

Sequence:MEPPAGAAATVKDPDHDPVKTKVSAPAADPKPRTSSQKAGHSLQDWDTIATVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKPPIVPKLSGDGDISNFETYPESELDKTPSVSDKDLETFKNF

Tissue specificity:Widely expressed. {ECO:0000269|PubMed:10729225}.

Induction:

Developmental stage:Expressed in central nervous system and heart tissues in early development stages and in most organs at later stages (at protein level). Detected in embryos from 9 dpc onward with higher expression in differentiating neuronal tissues at 11.5 dpc. {ECO:0000269|PubMed:10729225, ECO:0000269|PubMed:15879576}.

Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily


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