NKX26_MOUSE P43688
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UniProt:P43688
Recommended name：Homeobox protein Nkx-2.6
EC number：
Alternative names：(Homeobox protein NK-2 homolog F)
Cleaved into：
GeneID：18092
Gene names (primary )：Nkx2-6
Gene names (synonym )：Nkx-2.6 Nkx2f
Gene names (ORF )：
Length：289
Mass：31597
Sequence：MLSSPVASTPFSVADILRLECQQKDSKTLSQWELHRNPVKPRYLRMNQESGWFESSDRAQAVPFRCTWETVLEMGSNPVGEPQTPPGTISRLGARNPMTDRGVGNLSGDMRRGGPVSTRTRPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLASALQLTSTQVKIWFQNRRYKSKSQRQDQTLELAGHPLAPRRVAVPVLVLDGKPCLDPDVAAFLGPYKATSPYSCFGGYAGTPYDASYASRCTSASAGPGPLTPLASSGFSPGGQSAAPQGHLPATPQGVTAW
Tissue specificity：Not detected in any neonate or adult tissues. {ECO:0000269|PubMed:10733590}.
Induction：
Developmental stage：Expressed in developing gut endoderm, cardiac progenitors and heart. Expression restricted to the very narrow development period between stages 8.0 and 11.5 dpc. First detected at 8.0 dpc in the endoderm of the lateral walls and lip of the forming foregut pocket, directly juxtaposed to cardiogenic mesoderm. At 8.5 dpc, expressed in the forming pharynx, predominantly in its lateral aspects where pouches will form. From 8.5 to 11.5 dpc, expressed in the ventrolateral endoderm of all forming pouches, as well as in juxtaposed arch ectoderm and mesenchyme. Expression levels decrease as pouches matured. Also expressed in the ventral hindgut endoderm from 9.5 dpc and in a short segment at the foregut-midgut junction spanning the proximal parts of the common bile and pancreatic ducts. {ECO:0000269|PubMed:9486544, ECO:0000269|PubMed:9545560}.
Protein families：NK-2 homeobox family