TX19A_MOUSE Q99MV2
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UniProt:Q99MV2
Recommended name：Testis-expressed protein 19.1
EC number：
Alternative names：(mTex19.1) (Testis-expressed protein 19A)
Cleaved into：
GeneID：73679
Gene names (primary )：Tex19.1
Gene names (synonym )：Tex19 Tex19a
Gene names (ORF )：
Length：351
Mass：40401
Sequence：MCPPVSVRHGARGMSCLYEAWLYHLVHGEQTKICFACFKAAFLLNKLYLEMGDWQEEEEEEEEEDADLLEYLSESESESEQEPGPEQDAWRGLGSLYVPQSVSEGSGVLLPTPVWTQGILFSIFVPTELFPQEAVPLDLGPEDAEWTQALPWRLDGLFPCSHQLIPPLTWWDIFDVMPSPGQPVLLELRCHWPLDQTVAQSWLQDQKFVLLLDSVQSRCHLLSMRVRWVVRTQVQHWQVLLDPGEMWVAHFRKEVGQHGLYHQSLNPWRLSILTASELGMELLPATCYLWNKGFWVGSFLPWHINMPETWSWEPGERLFITDATICGTDYHLAQSFLDSHPTPHPLLTLTP
Tissue specificity：Expressed in testis, placenta and ovary. Expressed in pluripotent stem cells. In testis, expression is highest in mitotic spermatogonia, decreases as spermatocytes progress through meiosis, and is present at low levels in round spermatids (at protein level). {ECO:0000269|PubMed:18096721, ECO:0000269|PubMed:18802469, ECO:0000269|PubMed:22447323, ECO:0000269|PubMed:28254886}.
Induction：Expression is down-regulated by DAZL protein, which binds to 3'UTR of Tex19.1 mRNAs and probably represses its translation. {ECO:0000269|PubMed:19247806}.
Developmental stage：Expressed in early embryo and is later limited to the germ line. Expressed in the ectoderm and then in primordial germ cells (PGCs). Expressed in testis from 13.5 dpc to adulthood in gonocytes and spermatocytes. Also present in the developing and adult ovary as well as in the placenta and its precursor tissue, the ectoplacental cone. {ECO:0000269|PubMed:18096721}.
Protein families：