PLK2_MOUSE P53351
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UniProt:P53351
Recommended name：Serine/threonine-protein kinase PLK2
EC number：EC 2.7.11.21
Alternative names：(Polo-like kinase 2) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase)
Cleaved into：
GeneID：20620
Gene names (primary )：Plk2
Gene names (synonym )：Snk
Gene names (ORF )：
Length：682
Mass：77812
Sequence：MELLRTITYQPAAGTKMCEQALGKACGGDSKKKRPQQPSEDGQPQAQVTPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKNFFKKAAAALFGGKKDKARYNDTHNKVSKEDEDIYKLRHDLKKVSITQQPSKHRADEEPQPPPTTVARSGTSAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICNQSEEYLLTYINEDRISTTFRLTTLLMSGCSLELKNRMEYALNMLLQRCN
Tissue specificity：Brain, lung and heart. {ECO:0000269|PubMed:1508211}.
Induction：Directly regulated by p53/TP53. Induced by serum and phorbol ester. {ECO:0000269|PubMed:12897130, ECO:0000269|PubMed:1508211}.
Developmental stage：Expressed in early G1, during G0-G1 transition as well as in cycling cells. {ECO:0000269|PubMed:12651910}.
Protein families：Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily