PEG10_MOUSE   Q7TN75


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UniProt:Q7TN75

Recommended name:Retrotransposon-derived protein PEG10

EC number:

Alternative names:(Embryonal carcinoma differentiation regulated protein) (Mammalian retrotransposon-derived protein 2) (Myelin expression factor 3) (MyEF-3) (Myelin expression factor 3-like protein 1) (MEF3-like protein 1) (Paternally expressed gene 10 protein) (Retrotransposon gag domain-containing protein 3) (Retrotransposon-derived gag-like polyprotein) (Ty3/Gypsy-like protein)

Cleaved into:

GeneID:170676

Gene names  (primary ):Peg10

Gene names  (synonym ):Edr Mar2 Mart2 Mef3l1 Rgag3

Gene names  (ORF ):

Length:958

Mass:109849

Sequence:MAAAGGSSNCPPPPPPPPPNNNNNNNTPKSPGVPDAEDDDERRHDELPEDINNFDEDMNRQFENMNLLDQVELLAQSYSLLDHLDDFDDDDEDDDFDPEPDQDELPEYSDDDDLELQGAAAAPIPNFFSDDDCLEDLPEKFDGNPDMLGPFMYQCQLFMEKSTRDFSVDRIRVCFVTSMLIGRAARWATAKLQRCTYLMHNYTAFMMELKHVFEDPQRREAAKRKIRRLRQGPGPVVDYSNAFQMIAQDLDWTEPALMDQFQEGLNPDIRAELSRQEAPKTLAALITACIHIERRLARDAAAKPDPSPRALVMPPNSQTDPTEPVGGARMRLSKEEKERRRKMNLCLYCGNGGHFADTCPAKASKNSPPGKLPGPAVGGPSATGPERIRSPPSEASTQHLQVMLQIHMPGRPTLFVRAMIDSGASGNFIDQDFVIQNAIPLRIKDWPVMVEAIDGHPIASGPIILETHHLIVDLGDHREILSFDVTQSPFFPIVLGIRWLSTHDPHITWSTRSIVFNSDYCRLRCRMFAQIPSNLLFTVPQPNLHPYLLHHVHPHVHPHMHQHLHQHLHQFLHPDPHQYPHPDPHYHHHQQADMQHQLQQYLYQYLYYHLYPVMHHHLPPDQHEHLHEYLHQYLHQYLHQFLHHHLHPDLHQYLYQYLHNHMNPDPHHHPHPDPPQDPHHPPHQDPHQHPDPHQDPPHQDPHQDAHQDPHMDPHLHQHQHPQPQPHPQQHPNHPQQPPFFYHMAGFRIYHPVRYYYIQNVYTPVDEHVYPGHRVVDPNIEMIPGAHSLPSGHLYSMSESEMNALRNFVDRNVKDGLMTPTVAPNGAQVLQVKRGWKLQVTYNCRAPQSGTIQNQYLRMSLPNMGDPAHLASYGEFVQVPGYPYPAYVYYTSPHMMTAWYPVGRDVHGRIIVVPVVITWSQNTNRQPPVPQYPPPQPPPPPPPPPPPPPPPPASSCSAA

Tissue specificity:Expressed in brain and testis. Expressed during the early process of adipocyte differentiation. Expressed weakly in mammary gland but strongly in breast carcinomas of a c-MCY-driven transgenic model. {ECO:0000269|PubMed:11574691, ECO:0000269|PubMed:16423995, ECO:0000269|PubMed:17707377}.

Induction:Up-regulated by MYC and during adipocyte differentiation. {ECO:0000269|PubMed:16423995, ECO:0000269|PubMed:17707377}.

Developmental stage:Expressed in embryo, placenta and amniotic membrane at 10.5 dpc. Expressed in placenta at 9.5 dpc and appeared to increase as gestation progresses peaking around 12.5 and 15.5 dpc (at protein level). Expressed in embryo at 9.5, 12.5 and 16.5 dpc. Expressed in developing musculo-skeletal system, during skeletal myogenesis and also in precartilage primordia and derivative chondrogenic cells of the developing skeleton. Expressed in mesenchymal tissues of developing lung, kidney, gonad, gut and placenta. Not expressed at stages of chondrocyte hypertrophy and ossification of bones. Expressed in all extraembryonic tissues at 9.5 and 12.5 dpc and low-level expression in the embryonic brain and vertebral cartilage at 12.5 dpc. {ECO:0000269|PubMed:11574691, ECO:0000269|PubMed:16341224, ECO:0000269|PubMed:17942406}.

Protein families:


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