DIXC1_MOUSE Q80Y83
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UniProt:Q80Y83
Recommended name：Dixin
EC number：
Alternative names：(Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)
Cleaved into：
GeneID：330938
Gene names (primary )：Dixdc1
Gene names (synonym )：Ccd1 Kiaa1735
Gene names (ORF )：
Length：711
Mass：80215
Sequence：MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVGQLALDSDASVDERTDFFLLHSPFKAAGEKLTGVQLSPSNQQEMKSNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSKAPVQSHQPHCATAVAQGAAAALADVCHDVSRSGRDVFRYRQRNASVDGEIENPYWSVRALVQQYEGQQKSPSESSCSSLTSPSPIHSAKSESIITQAEEKADFVIIPSEGIENRTDEPDSPSSRDWRPGSRGTYLEATWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPVALCEPGVNPEEQLIIIRSRLDQSVEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLFQQQQAKLEEALRKLSDASYQQVDLERELEQKDVLLAHCMKGETDEVTNYNSHSSQRNGFVLPVAGRGATTVTHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVVETQKKQERKVGGRSPRNQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN
Tissue specificity：Abundantly expressed in brain and testis and to a lower extent in lung, kidney, colon, ovary and urinary bladder. Expressed in brain, liver, testis and spleen (at protein level). Expressed throughout the brain with strong expression in main and accessory olfactory bulbs, cerebral cortex, piriform cortex, hippocampus, habenular nucleus, dorsal thalamus, superior and inferior colliculi and cerebellum. {ECO:0000269|PubMed:15857680}.
Induction：
Developmental stage：Expressed in embryonic brain, liver and spleen (at protein level). First detected at 7.5 dpc in the node. Expressed in the cephalic mesenchyme and tail bud at 8.5 dpc, and in the branchial arch and forelimb bud at 9.5 dpc. In the central nervous system, expression begins and persists in the regions where the neurons differentiate. Expression is also strong in the peripheral nervous system, including sensory cranial ganglia, dorsal root ganglia, and autonomic ganglia, and in the sensory organs, such as the inner nuclear layer of the neural retina, saccule and cochlea of the inner ear, and nasal epithelium. Outside the nervous system, expression is detected in the cartilage, tongue, lung bud, stomach, and gonad from 12.5 dpc to 14.5 dpc, and in the tooth bud, bronchial epithelium, and kidney at 17.5 dpc. {ECO:0000269|PubMed:15857680, ECO:0000269|PubMed:16378754}.
Protein families：DIXDC1 family