WDR11_MOUSE Q8K1X1
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UniProt:Q8K1X1
Recommended name：WD repeat-containing protein 11
EC number：
Alternative names：(Bromodomain and WD repeat-containing protein 2)
Cleaved into：
GeneID：207425
Gene names (primary )：Wdr11
Gene names (synonym )：Brwd2 Kiaa1351
Gene names (ORF )：
Length：1223
Mass：135937
Sequence：MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSNTAQTLQVLEKHKADIVKVRWARENYHHNIGSPYCLRLASADVTGKIIVWDVAAGVAQCEIQEHVKPIQDVQWLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEGIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLAAATGAKKALNKVKILITQEKPSADFVALNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCSQRDGLFCLHENGCITLRVRRSYNSICTTSNDEPDLDPVQELTYDLRSQCDAIRVTKTVRPFSMVCCPVNENAAALIVSDGRVMIWELKSAVCSRNARNSSGVSPLYSPVSFCGIPGGVLQNKLPDLSLDNMIGQSAIAGEEHPKGSILQEVHLKFLLTGLLSGLPSPQFAIRMCPPLTTKNIKTYQPLLAVGTSNGSVLVYHLTSGLLHKELSVHSCEVKGIEWTSLTSFLSFAASTPNNMGLVRNELQLVDLPTGRSTAFRGDRGNDESPIEMIKVSHLKQYLAVVFKDKPLELWDIRTCTLLREMSKSFPAITALEWSPSHNLKSLRKKQLATREAMARQTVVSDAELGAVESSVISLLQEAESKAELSQNISAREHFVFTDNDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKARVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSTCFRMDEQELVEPVWCPYLLVPRAALALKAFLLHQPWNGRYSLDISHIDYPENEEIKTLLQEQLHALSNDIKKLLLDPDFSLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQAKSGDTVVTKEGAPKDRLSNPLDICYDVLCENTYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLNSEECADVLKRWVDHLCSPQVNQKSKALLVLLSLGCFVSVAETLHSMRYFDRAALFVEACLKYGAFEVSEDTEKLIAAIYADYARSLKSLGFRQGAVRFASKAGAAGRDLLNELGSTKEELTES
Tissue specificity：Broadly expressed in various organs including brain, eye,ear, lung, heart, kideny and gonads (PubMed:29263200). Cerebral cortex. The entire developing central nervous system, except for the spinal cord, reveals expression. Expressed in the neuroepithelium, including the diencephalic region that gives rise to hypothalamic neurons. In the adult brain, intense expression is restricted to the olfactory bulb, the olfaction-related piriform cortex, the granule cell layer of the cerebellum, and neurons of the hippocampal formation. The brain demonstrated expression scattered throughout the hypothalamus, sometimes in clusters of neurons (PubMed:20887964). {ECO:0000269|PubMed:20887964, ECO:0000269|PubMed:29263200}.
Induction：
Developmental stage：Expressed in embryos from 10.5. to 14.5 dpc (PubMed:20887964, PubMed:29263200). In 10.5-12.5 dpc embryos, detected in the vesicles of the heart, branchial arches, mesonephric duct, head mesenchyme, developing eye and forebrain (PubMed:29263200). At 12.5 and 14.5 dpc, high levels of expression are particularly noteworthy in the developing cortex and the olfactory bulb (PubMed:20887964, PubMed:29263200). {ECO:0000269|PubMed:20887964, ECO:0000269|PubMed:29263200}.
Protein families：