CELF2_MOUSE   Q9Z0H4


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UniProt:Q9Z0H4

Recommended name:CUGBP Elav-like family member 2

EC number:

Alternative names:(CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (mETR-3) (Neuroblastoma apoptosis-related RNA-binding protein) (mNapor) (RNA-binding protein BRUNOL-3)

Cleaved into:

GeneID:14007

Gene names  (primary ):Celf2

Gene names  (synonym ):Cugbp2 Napor

Gene names  (ORF ):

Length:508

Mass:54271

Sequence:MRCPKSAVTMRNEELLLSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLSSTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY

Tissue specificity:Expressed in tongue, spleen and brain (at protein level). Expressed in liver, thigh, stomach, lung and heart to very low levels (at protein level). Expressed in heart, brain, lung and muscle. {ECO:0000269|PubMed:10524244, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:15358864, ECO:0000269|PubMed:15830352}.

Induction:Up-regulated following ionizing radiation in the crypt epithelial cells of the intestin. Down-regulated by bacterial lipopolysaccharides (LPS). Down-regulated by prostaglandin E2 following ionizing radiation. {ECO:0000269|PubMed:12535526, ECO:0000269|PubMed:15358864}.

Developmental stage:Expressed in heart, muscle, brain, liver, thigh, stomach and lung at 14 dpc (at protein level). Expressed in embryo at 7, 11 and 17 dpc. Expressed in the developing central nervous system from 12 to 16 dpc. {ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:15830352}.

Protein families:CELF/BRUNOL family


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