NUMBL_MOUSE   O08919


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UniProt:O08919

Recommended name:Numb-like protein

EC number:

Alternative names:

Cleaved into:

GeneID:18223

Gene names  (primary ):Numbl

Gene names  (synonym ):Nbl

Gene names  (ORF ):

Length:604

Mass:64130

Sequence:MSRSAAASGGPRRPDQHLSPAPCGASGPPETFRTESDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAGDKKKAEAAAAPAVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGTGDSDGINALCTQISSSFASAGAPASGPPPATTGTSAWGEPSVPAAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQATSVPPMPTMAPTLQPFSAPVGPFDTAAAQVAVFLPPTHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAAPSAPGGQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKPAVEKPSNPFSGDLQKTFEIEL

Tissue specificity:Preferentially expressed in the nervous system. In the developing neocortex, expressed in postmitotic neurons in the cortical plate but not in progenitors within the ventricular zone. {ECO:0000269|PubMed:9169836}.

Induction:

Developmental stage:Expressed in neural progenitor and neuron cells throughout the developing nervous system. Expressed in somites and throughout the neural tube from 8.5 dpc, onward. {ECO:0000269|PubMed:12410312, ECO:0000269|PubMed:15273690, ECO:0000269|PubMed:9169836}.

Protein families:


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