NAV1_MOUSE Q8CH77
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8CH77
Recommended name：Neuron navigator 1
EC number：
Alternative names：(Pore membrane and/or filament-interacting-like protein 3)
Cleaved into：
GeneID：215690
Gene names (primary )：Nav1
Gene names (synonym )：Kiaa1151 Pomfil3
Gene names (ORF )：
Length：1875
Mass：202368
Sequence：MLGSSVKSVQPEVELSGGSGSGGDEGADESRGASRKAAAADGRGMLPKRAKAAGGSGSMAKASAAELKVFKSGSVDSRVPGGLPTSNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKLGPKGRETPLMSKTLSKSEHSLFQPKGGSTGGAKTPLAPLAPSLGKPSRIPRGPYAEVKPLSKAPEAAVSDDGKSDDELLSSKAKAQKGSGTVPSAKGQEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMPCYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGPPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPTTPTASRRSSTIVLRTDSEKRSLAESGLNWFSESEEKTPKKLEYDSGSLKMEPGTSKWRRERPESCDDASKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGSSATLSKIQKSSGIPVKPVNGRKTSLDVSNSVEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPSKVASGRSTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPPATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTHASKVPDLHAPSSSTGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSAPIPTPPTAPSEEDTEELPWSGSPRAGQLDSSQRDRNTLPKKGLRYQLQSQEETKERRHSHTAGGLPESDDQAELPSPPALSMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASEATPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTEVTETPAHSVPHTRLFQANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGCTPGQVPGSSALSSPRRSLGLALSHPFSPSLTDTDLSPMDGISTCGSKEEVTLRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSLSHVKRVLDAEPPEMPPCRRGVNNISVALKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTDGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPSVGPHSTASPPEDRTVKDSTPNSLDSDPLMAMLLKLQEAANYIESPDRETILDPNLQATL
Tissue specificity：Expressed in heart and brain. Present in brain (at protein level). In adult brain, found almost exclusively in areas of secondary neurogenesis from the hippocampus and the subventricular zone. {ECO:0000269|PubMed:15797708}.
Induction：
Developmental stage：Expressed in neural structures at 10 dpc. At 13 dpc and 15 dpc, highly expressed in neural tube, somites, heart and dispersed cells in tongue and face. At P5, widely expressed through the central nervous system in post-mitotic post-migratory zones. Brain expression decreases rapidly from P5 to P21 (at protein level). {ECO:0000269|PubMed:12062803, ECO:0000269|PubMed:15797708}.
Protein families：Nav/unc-53 family