MAFB_MOUSE P54841
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UniProt:P54841
Recommended name：Transcription factor MafB
EC number：
Alternative names：(Maf-B) (Kreisler) (Segmentation protein Kr) (Transcription factor Maf-1) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)
Cleaved into：
GeneID：16658
Gene names (primary )：Mafb
Gene names (synonym )：Krml Maf1
Gene names (ORF )：
Length：323
Mass：35809
Sequence：MAAELSMGQELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFSPTEPKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQPLQSFDGFRSAHHHHHHHHPHPHHGYPGAGVTHDDLGQHAHPHHHHHHQASPPPSSAASPAQQLPTSHPGPGPHATAAATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGFREAGSTSDSPSSPEFFL
Tissue specificity：Expressed in pancreatic alpha-cells (glucagon-positive cells), in podocytes of the kidney and macrophages (at protein level). Most abundant in kidney, gut, lung and brain. {ECO:0000269|PubMed:16443760, ECO:0000269|PubMed:16847325, ECO:0000269|PubMed:17901057}.
Induction：
Developmental stage：Expressed in pancreatic alpha-cells at 10.5 dpc. Expressed in insulin and glucagon islet progenitor cells at 12 dpc onwards (at protein level). Detectable at 8.0 dpc (one somite) as a band in the caudal hindbrain and by 8.5 dpc (six to eight somites) as a sharp rostral edge coincident with the rhombomeres (r) 4 and 5 boundary and a diffuse caudal edge located midway through r6. Expressed in the lens epithelial cells at 10.5 to 14.5 dpc. {ECO:0000269|PubMed:10383433, ECO:0000269|PubMed:16443760, ECO:0000269|PubMed:17901057}.
Protein families：BZIP family, Maf subfamily