SHSA7_MOUSE Q8C3Q5
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UniProt:Q8C3Q5
Recommended name:Protein shisa-7
EC number:
Alternative names:(Cystine-knot AMPAR modulating protein of 59 kDa) (CKAMP59) (GABA(A) receptor auxiliary subunit Shisa7) (Shisa family member 7)
Cleaved into:
GeneID:232813
Gene names (primary ):Shisa7
Gene names (synonym ):
Gene names (ORF ):
Length:558
Mass:58334
Sequence:MPALLLLGTVALLASAAGPAGARPSNDTSSVAPGPLPALLAHLRRLTGALAGGGSAAGTSANATKTSPASGTGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRAGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHREINVPRALVDILRHQAGPATRPDRARSSSLTPGLGGPDSMAPRTPKNLYNTMKPSNLDNLHYNVNSPKHHAATLDWRAMPPPSPSLHYSTLSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRQLEMPRGTLPLHALRRPGTGGGYRMDGWGGPEELGLAPAPNPRRVMSQEHLLGDGSRASRYEFTLPRARLVSQEHLLLSSPEALRQSREHLLSPPRSPALPPDPTTRASLAASHSNLLLGPGGPPTPLHGLPPSGLHAHHHHALHGSPQPAWMSDAGGGGGTLARRPPFQRQGTLEQLQFIPGHHLPQHLRTASKNEVTV
Tissue specificity:Mainly expressed in neurons (PubMed:26623514, PubMed:29199957, PubMed:31601770). Highly expressed in brain structures including cortex, striatum, olfactory bulb, amygdala hippocampus CA1-3 and dentate gyrus (at protein level) (PubMed:26623514, PubMed:29199957, PubMed:31601770). {ECO:0000269|PubMed:26623514, ECO:0000269|PubMed:29199957, ECO:0000269|PubMed:31601770}.
Induction:
Developmental stage:Expressed in the cerebral cortex on 17 dpc and in olfactory bulb and hippocampus on postnatal day 1 (P1) (PubMed:26623514). Expression in hippocampus increases during postnatal development and reaches a plateau after 3 weeks (PubMed:29199957). Expression is high during prenatal development and decreases in the thalamus and brainstem during postnatal development (PubMed:26623514). {ECO:0000269|PubMed:26623514, ECO:0000269|PubMed:29199957}.
Protein families:Shisa family