MB212_MOUSE Q8BPP1
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UniProt:Q8BPP1
Recommended name：Protein mab-21-like 2
EC number：
Alternative names：
Cleaved into：
GeneID：23937
Gene names (primary )：Mab21l2
Gene names (synonym )：
Gene names (ORF )：
Length：359
Mass：40907
Sequence：MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL
Tissue specificity：Expressed in the adult cerebellum and eye, with lower levels in the adult forebrain (PubMed:10556287). In embryos at 10.5 days post-coitum strongly expressed in the rostral and distal regions of the developing neural retina, with no expression immediately adjacent to the closing optic fissure. Expression is also observed in the dorsal and ventral aspects of the developing forelimb bud and in the developing pharyngeal arches, as well as in the midbrain (PubMed:24906020). {ECO:0000269|PubMed:10556287, ECO:0000269|PubMed:24906020}.
Induction：
Developmental stage：Expressed in the developing dorsal midbrain, the posterior portion of the mesencephalon and the retinal primordium of the optic cup. At 10 dpc, expressed in the temporal and nasal aspect of the retina and throughout the length of the dorsal midbrain. At 10.5 dpc this retinal pattern of expression persists, and extraneural sites of expression include the branchial region, limb buds and intestine. Also highly expressed in the alar mesencephalon and the rhombencephalic basal plate from 10.5 dpc to 14.5 dpc, and in the posterior third of the tectum and the presumptive gut wall. Also strongly expressed in the hindbrain, optic vesicle, maxillary and mandible process, paraxial mesoderm, developing digits and the umbilical cord. {ECO:0000269|PubMed:10495284, ECO:0000269|PubMed:10556287, ECO:0000269|PubMed:11857508, ECO:0000269|PubMed:12642482, ECO:0000269|PubMed:15385160}.
Protein families：Mab-21 family