LGR6_MOUSE Q3UVD5
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UniProt:Q3UVD5
Recommended name:Leucine-rich repeat-containing G-protein coupled receptor 6
EC number:
Alternative names:
Cleaved into:
GeneID:329252
Gene names (primary ):Lgr6
Gene names (synonym ):
Gene names (ORF ):
Length:967
Mass:104267
Sequence:MHSPPGLLALWLCAVLCASARAGSDPQPGPGRPACPAPCHCQEDGIMLSADCSELGLSVVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPLAIRTLGRLQELGFHNNNIKAIPEKAFMGSPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSLNGATDIQEFPDLKGTTSLEILTLTRAGIRLLPPGVCQQLPRLRILELSHNQIEELPSLHRCQKLEEIGLRHNRIKEIGADTFSQLGSLQALDLSWNAIRAIHPEAFSTLRSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCAYGICASFFKTSGQWQAEDFHPEEEEAPKRPLGLLAGQAENHYDLDLDELQMGTEDSKPHPSVQCSPVPGPFKPCEHLFESWGIRLAVWAIVLLSVLCNGLVLLTVFASGPSPLSPVKLVVGAMAGANALSGISCGLLASVDALTYGQFAEYGARWESGLGCQATGFLAVLGSEASVLLLTLAAVQCSISVTCVRAYGKAPSPGSVRAGALGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGRPAALGFAVALVMMNSLCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLWPSPRSPGPLAYAAAGELEKSSCDSTQALVAFSDVDLILEASEAGQPPGLETYGFPSVTLISRHQPGATRLEGNHFVESDGTKFGNPQPPMKGELLLKAEGATLAGCGSSVGGALWPSGSLFASHL
Tissue specificity:Specifically expressed in multipotent stem cells in the epidermis. {ECO:0000269|PubMed:20223988}.
Induction:
Developmental stage:Expressed in the earliest embryonic hair placodes. In adult hair follicles, present in a region directly above the follicle bulge. Specifically present in prenatal cells establishing the hair follicle, sebaceous gland and interfollicular epidermis. Postnatally, present in cells generating sebaceous gland and interfollicular epidermis (PubMed:20223988). During limb development, at 14.5 dpc, expressed in the ectoderm overlying the limb buds and at the apical ectodermal ridge. In the developing lungs, at 14.5 dpc, expressed in smooth muscle cells (PubMed:29769720). {ECO:0000269|PubMed:20223988, ECO:0000269|PubMed:29769720}.
Protein families:G-protein coupled receptor 1 family