TFEC_MOUSE Q9WTW4
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UniProt:Q9WTW4
Recommended name:Transcription factor EC
EC number:
Alternative names:(TFE-C) (mTFEC)
Cleaved into:
GeneID:21426
Gene names (primary ):Tfec
Gene names (synonym ):Tcfec
Gene names (ORF ):
Length:317
Mass:35144
Sequence:MTFDCRVCDQTLKRAQPPAASCMPLAEHEPMSPDSDAGCAGNPFTNLLALGKKDGAEKWHLSGSILDVYSDEQGISSANAGLTDAPCPSILPMRKEIAETDGRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLRLRIQELEIQARAHGLPILASLGTADVGTHITKQQTHPERNLGGCCLQLTPTQGTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAVSKASSRSSLSSEDGDEL
Tissue specificity:Expressed in osteoclast-like cells (at protein level). Expressed in cells of the mononuclear phagocyte lineage. Expressed in macrophages and in osteoclast-like cells. {ECO:0000269|PubMed:9973413}.
Induction:Up-regulated in bone marrow-derived macrophages by Th2 cytokines, IL-4, IL-13 and LPS. {ECO:0000269|PubMed:15908341}.
Developmental stage:Expressed in the early developing retinal pigmented epithelium and in the peripheral retina. {ECO:0000269|PubMed:15459106}.
Protein families:MiT/TFE family