SH3R1_MOUSE Q69ZI1
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UniProt:Q69ZI1
Recommended name：E3 ubiquitin-protein ligase SH3RF1
EC number：EC 2.3.2.27
Alternative names：(Plenty of SH3s) (Protein POSH) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Cleaved into：
GeneID：59009
Gene names (primary )：Sh3rf1
Gene names (synonym )：Kiaa1494 Posh Posh1 Sh3md2
Gene names (ORF )：
Length：892
Mass：93447
Sequence：MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVDELPSNILLVRLLDGIKQRPWKPGPGGGGGTTCTNTLRAQGSTVVNCGSKDLQSSQCGQQPRVQAWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVSGVHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDTAECPSATAQSTSASKHPDTKKNTRKRHSFTSLTMANKSSQGSQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTPPPSSPVTTGPAFTFPSDVPYQAALGSMNPPLPPPPLLAATVLASTPSGATAAVAAAAAAAAAAGMGPRPVMGSSEQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVSMSTAGQASRGVTMVSPSTAGGPTQKPQGNGVAGNPSVVPTAVVSAAHIQTSPQAKVLLHMSGQMTVNQARNAVRTVAAHSQERPTAAVTPIQVQNAACLGPASVGLPHHSLASQPLPPMAGPAAHGAAVSISRTNAPMACAAGASLASPNMTSAMLETEPSGRTVTILPGLPTSPESAASACGNSSAGKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLDVELGAGEAPLQGAVGPELPLGGSHGRVGSCPTDGDGPVAAGTAALAQDAFHRKTSSLDSAVPIAPPPRQACSSLGPVMNEARPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
Tissue specificity：Ubiquitously expressed. {ECO:0000269|PubMed:9482736}.
Induction：
Developmental stage：Expressed in the embryonic brain. Expressed strongly in the venricular zone (VZ), subventricular zone (SVZ), and lower intermediate zone (IZ) but weakly in the upper IZ and cortical plate (CP) at 14.5 dpc. At 16.5 dpc, expression increases in the IZ and CP. At 18.5 dpc, it increases significantly in the CP but decreases in the IZ, SVZ, and VZ (at protein level). {ECO:0000269|PubMed:22959435}.
Protein families：SH3RF family