EFNB1_MOUSE P52795
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UniProt:P52795
Recommended name：Ephrin-B1
EC number：
Alternative names：(CEK5 receptor ligand) (CEK5-L) (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (Stimulated by retinoic acid gene 1 protein)
Cleaved into：Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)
GeneID：13641
Gene names (primary )：Efnb1
Gene names (synonym )：Epl2 Eplg2 Lerk2 Stra1
Gene names (ORF )：
Length：345
Mass：37859
Sequence：MARPGQRWLSKWLVAMVVLTLCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNKPHQEIRFTIKFQEFSPNYMGLEFKKYHDYYITSTSNGSLEGLENREGGVCRTRTMKIVMKVGQDPNAVTPEQLTTSRPSKESDNTVKTATQAPGRGSQGDSDGKHETVNQEEKSGPGAGGGGSGDSDSFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
Tissue specificity：Expressed on lateral floor plate cells, specifically on commissural axon segments that have passed through the floor plate. Expressed in cells of the retinal ganglion cell layer during retinal axon guidance to the optic disk (PubMed:10704386). Expressed in myogenic progenitor cells (PubMed:27446912). {ECO:0000269|PubMed:10704386, ECO:0000269|PubMed:27446912}.
Induction：
Developmental stage：Expressed in the floor plate throughout the period of commissural axon pathfinding (PubMed:10704386). In myogenic progenitor cells, highly expressed during early development (11.5 dpc) and progressively repressed as developments proceeds (PubMed:27446912). {ECO:0000269|PubMed:10704386, ECO:0000269|PubMed:27446912}.
Protein families：Ephrin family