POPD1_MOUSE   Q9ES83


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UniProt:Q9ES83

Recommended name:Blood vessel epicardial substance

EC number:

Alternative names:(mBVES) (Popeye domain-containing protein 1) (Popeye protein 1)

Cleaved into:

GeneID:23828

Gene names  (primary ):Bves

Gene names  (synonym ):Pop1 Popdc1

Gene names  (ORF ):

Length:358

Mass:41016

Sequence:MNSTESIPLAQSTVAGFTSELESLTPVPSNETTCENWREIHHLVFHVANVCFAVGLLIPTTLHLHMILLRVMLSLGCTLYVVWATLYRCALDVMIWNSVFLGINILHLSYLLYKKRPVKIEKELGGVYHRLFEPLRVPPDLFRRLTGQFCMIQTLKRGQVYATEDKTSVDDRLSILLKGRMKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIVADDNCRFLCWSRERLTYFLESEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKVKKLEPQMSLCTQISMLEMRNSITSSSDGEDGLHHFLRGSSSTASLPMSSPQQRASAKMKPIEEGVEDDDEVFVSPDALKVHQLP

Tissue specificity:Expressed in epithelial cells, skeletal muscle, heart and intestinal smooth muscle (at protein level). Expressed in fetal and adult heart and skeletal muscle. {ECO:0000269|PubMed:10882522, ECO:0000269|PubMed:11839816, ECO:0000269|PubMed:16188940, ECO:0000269|PubMed:18541910}.

Induction:

Developmental stage:Expressed in the mesoderm of the cardiac crescent at 9.5 dpc. Expressed in cardiac myocytes of the sinoatrial compartment and some restricted areas of the dorsal part of the ventricle chambers at 10.5 dpc and 12.5 dpc. Expressed in branchial arches, myotome and in a posterior domain in the limb at 10.5 dpc. Expressed in the heart, mainly in the compact layer myocardium, peridigital mesenchyme, the somites of the tail bud, the smooth muscle cells of the trachea and the developing bronchial tree, the smooth muscle cells lining the digestive tract, the dorsal root ganglia and the pancreas anlage at 13.5 dpc (at protein level). Expressed in the sinoatrial compartment and some restricted areas in the dorsal part of the ventricle at 9.5 dpc, 10.5 dpc and 11.5 dpc. At 12.5 dpc, expression was observed in the ventral half of the ventricle where it was limited to the subepicardial compact layer. {ECO:0000269|PubMed:10882522, ECO:0000269|PubMed:11839816}.

Protein families:Popeye family


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