TY3H_MOUSE   P24529


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UniProt:P24529

Recommended name:Tyrosine 3-monooxygenase

EC number:EC 1.14.16.2

Alternative names:(Tyrosine 3-hydroxylase) (TH)

Cleaved into:

GeneID:21823

Gene names  (primary ):Th

Gene names  (synonym ):

Gene names  (ORF ):

Length:498

Mass:55993

Sequence:MPTPSASSPQPKGFRRAVSEQDTKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAVASAEPGNPLEAVVFEERDGNAVLNLLFSLRGTKPSSLSRALKVFETFEAKIHHLETRPAQRPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGEPIPHVEYTKEEIATWKEVYATLKGLYATHACREHLEAFQLLERYCGYREDSIPQLEDVSHFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRRSLEGVQDELHTLTQALSAIS

Tissue specificity:Expressed in the adrenal gland (PubMed:1674869). Expressed in the retina (PubMed:30936473). {ECO:0000269|PubMed:1674869, ECO:0000269|PubMed:30936473}.

Induction:

Developmental stage:Expressed in the retinal inner nuclear layer and outer nuclear layer at postnatal day 8 (P8) (PubMed:30936473). Expressed in retinal dopaminergic amacrine cells in the retina at P8 and P15 (PubMed:30936473). {ECO:0000269|PubMed:30936473}.

Protein families:Biopterin-dependent aromatic amino acid hydroxylase family


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