FGF13_MOUSE P70377
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UniProt:P70377
Recommended name：Fibroblast growth factor 13
EC number：
Alternative names：(FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)
Cleaved into：
GeneID：14168
Gene names (primary )：Fgf13
Gene names (synonym )：Fhf2
Gene names (ORF )：
Length：245
Mass：27588
Sequence：MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSEHFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
Tissue specificity：Detected in brain, eye and heart. In brain, the different isoforms display different patterns of expression. Expressed in brain and heart (at protein level). Isoform 3 is highly expressed in cardiac myocytes while isoform 1 is the most abundant in brain. {ECO:0000269|PubMed:10644718, ECO:0000269|PubMed:21817159, ECO:0000269|PubMed:9232594}.
Induction：
Developmental stage：Expressed in the subplate of the embryonic cortex and the axonal tracts in the intermediate zone, and in axonal tracts of projection neurons, specifically in the corticothalamic tract and the corpus callosum (at protein level). Isoform 2 is transiently expressed in the neocortex and hippocampus from 17 dpc to P7 (at protein level). In embryonic brain, present in all divisions of the central and peripheral nervous system and it is at least 5 times more abundant than other FHFs. Detected in the subplate, ganglionic eminences, and proliferative zones of the cortical wall at 14 dpc. Detected in the cortical plate of the cerebral cortex, hippocampus, and striatum from 17 dpc to P14. Expression is markedly reduced in adult brain where it is most abundant in hippocampus. Also detected in developing kidney. Expressed in developing chandelier neurons. {ECO:0000269|PubMed:30679375, ECO:0000269|PubMed:9232594}.
Protein families：Heparin-binding growth factors family