SOX30_MOUSE Q8CGW4
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UniProt:Q8CGW4
Recommended name:Transcription factor SOX-30
EC number:
Alternative names:
Cleaved into:
GeneID:214105
Gene names (primary ):Sox30
Gene names (synonym ):
Gene names (ORF ):
Length:782
Mass:83938
Sequence:MERARPEPPPPPPPPPRQPPRPTPPRPLRPAPPAQPVEAATFRAAAAERSQSPSAQATAAMAAVASSCGEAAAAGAQAAGTRRLLQVKPEQVLLLPPGGPGVPPAPDEGAAAAAAAAAAAASSAQARLLQLRPELLLLPPQSAADGGPCRPELHPMQPRTLLVKAEKQELGAGLDLSVGSRRTTEAGPRASRAAKLDGTGKALDGRRSDEKKAKLEAEEAPRDALKGGEGKSLLAIGEGVIKTEEPDRPRDDCRLGTEATSNGLVHSSKEAILAQPPSAFGPHQQDLRFPLTLHTVPPGARIQFQGPPPSELIRLSKVPLTPVPIKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTIYPYRSPTYSVVIPGLQNTITHPVGEAPPAIQLPTPAVQRPSPITLFQPSVSSTGPVAVPPPSLTPRPSLPPQRFSGPSQTDIHRLPSGSSRSVKRSTPGSLESTTRIPAGASTAHARFATSPIQPPKEYASVSTCPRSTPIPPATPIPHSHVYQPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLGYYEDRYQKHEAIFSALNRDYPFRDYPDEHTHSEDSRSCESMDGPPYYSSHGHGGEEYLNAMPTLDIGALENVFTAPASAPSGVQQVNVTDSDEEEEEKVLRNL
Tissue specificity:Expressed in the lung (at protein level) (PubMed:29739711). Expressed in testes (at protein level) (PubMed:10359848, PubMed:29848638). Expressed in preleptotene spermatocytes, round spermatids, and elongated spermatids in the testis (at protein level) (PubMed:29866902). Expressed in pachytene spermatocytes during stages 3 to 8 of spermatogenesis (at protein level) (PubMed:29866902, PubMed:29848638). Increased expression in diplotene spermatocytes at stage 9-11 and in metaphase spermatocytes or secondary spermatocytes at stage 12 (PubMed:29848638). Expressed in ovaries (PubMed:29848638). {ECO:0000269|PubMed:10359848, ECO:0000269|PubMed:29739711, ECO:0000269|PubMed:29848638, ECO:0000269|PubMed:29866902}.
Induction:Induced in germline stem cells by retinoic acid. {ECO:0000269|PubMed:29848638}.
Developmental stage:Expressed in the testes at 13.5 dpc (PubMed:10359848, PubMed:29848638). Also expressed in the mesonephros, metanephros, brain, lung, heart and stomach at 13.5 dpc (PubMed:10359848). Expressed in the testes at 14.5 dpc (PubMed:29848638). Expressed in the ovary at 13.5 and 14.5 dpc (PubMed:29848638). Expressed weakly in the testes at postnatal day 14 (P14), strongly expressed from P21 onwards (PubMed:29866902). Expressed in the nucleus of pachytene spermatocytes in stages 5 to 6 of spermatogenesis (PubMed:29866902). Expressed in round spermatids and increased expression in pachytene spermatocytes in stages 7 to 8 of spermatogenesis (PubMed:29866902). Expressed in the nucleus of diplotene spermatocytes in stages 11 to 12 of spermatogenesis, however expression in the nuclei of spermatids is lost (PubMed:29866902). {ECO:0000269|PubMed:10359848, ECO:0000269|PubMed:29848638, ECO:0000269|PubMed:29866902}.
Protein families: