SC6A4_MOUSE   Q60857


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UniProt:Q60857

Recommended name:Sodium-dependent serotonin transporter

EC number:

Alternative names:(SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)

Cleaved into:

GeneID:15567

Gene names  (primary ):Slc6a4

Gene names  (synonym ):Htt Sert

Gene names  (ORF ):

Length:630

Mass:70048

Sequence:METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAGPGQISNGYSAVPSTSAGDEAPHSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLISTPGTLKERIIKSITPETPTEIPCGDIRMNAV

Tissue specificity:

Induction:Expressed in a circadian manner in the midbrain with a higher level expression seen during the dark phase (at protein level). {ECO:0000269|PubMed:22572884}.

Developmental stage:Expressed in the uncrossed ipsilateral retinal ganglion cells (iRGCs) of the peripheral ventrotemporal (VT) region segment in the retina at 16.5 dpc. {ECO:0000269|PubMed:20676059}.

Protein families:Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily


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