SC6A4_MOUSE Q60857
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UniProt:Q60857
Recommended name:Sodium-dependent serotonin transporter
EC number:
Alternative names:(SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)
Cleaved into:
GeneID:15567
Gene names (primary ):Slc6a4
Gene names (synonym ):Htt Sert
Gene names (ORF ):
Length:630
Mass:70048
Sequence:METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAGPGQISNGYSAVPSTSAGDEAPHSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLISTPGTLKERIIKSITPETPTEIPCGDIRMNAV
Tissue specificity:
Induction:Expressed in a circadian manner in the midbrain with a higher level expression seen during the dark phase (at protein level). {ECO:0000269|PubMed:22572884}.
Developmental stage:Expressed in the uncrossed ipsilateral retinal ganglion cells (iRGCs) of the peripheral ventrotemporal (VT) region segment in the retina at 16.5 dpc. {ECO:0000269|PubMed:20676059}.
Protein families:Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily