AKT1_MOUSE P31750
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UniProt:P31750
Recommended name：RAC-alpha serine/threonine-protein kinase
EC number：EC 2.7.11.1
Alternative names：(AKT1 kinase) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) (Thymoma viral proto-oncogene)
Cleaved into：
GeneID：11651
Gene names (primary )：Akt1
Gene names (synonym )：Akt Rac
Gene names (ORF )：
Length：480
Mass：55707
Sequence：MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
Tissue specificity：Widely expressed. Low levels found in liver with slightly higher levels present in thymus and testis. {ECO:0000269|PubMed:8437858}.
Induction：
Developmental stage：Expressed in trophoblast and vessel endothelial cells of the placenta and in the brain at 14.5 dpc (at protein level). {ECO:0000269|PubMed:12783884}.
Protein families：Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily