LIMK1_MOUSE P53668
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UniProt:P53668
Recommended name:LIM domain kinase 1
EC number:EC 2.7.11.1
Alternative names:(LIMK-1) (KIZ-1)
Cleaved into:
GeneID:16885
Gene names (primary ):Limk1
Gene names (synonym ):Limk
Gene names (ORF ):
Length:647
Mass:72793
Sequence:MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCECSVSLSHQYYEKDGQLFCKKDYWARYGESCHGCSEHITKGLVMVAGELKYHPECFICLACGNFIGDGDTYTLVEHSKLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSLGHGPVSDPSPLSSPVHTPSGQAASSARQKPVLRSCSIDTSPGTSSLASPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHLPLGPQLEQLERGFWETYRRGESSLPAHPEVPD
Tissue specificity:Highest expression in the nervous system, particularly in the spinal cord and the cranial nerve and dorsal root ganglia.
Induction:
Developmental stage:Expressed in ventral neural tube and axonal projections at 12.5 dpc-13 dpc (at protein level). {ECO:0000269|PubMed:16204183}.
Protein families:Protein kinase superfamily, TKL Ser/Thr protein kinase family