MPP4_MOUSE Q6P7F1
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UniProt:Q6P7F1
Recommended name：MAGUK p55 subfamily member 4
EC number：
Alternative names：(Discs large homolog 6) (mDLG6)
Cleaved into：
GeneID：227157
Gene names (primary )：Mpp4
Gene names (synonym )：Dlg6
Gene names (ORF )：
Length：635
Mass：72001
Sequence：MRQSDRGAELTNEDRALPTPPDPENGLSGILRLLLQELSLFYSRDVNGLCLLYDLLHSPWLQALLKVYDCLQRFKEKKLVPDTTHAQILACEVLELLPKASGSPEIQELRQVLQAPHCKALLSAHDTVAQKDFEPLLPPLPDNIPDSEEAMRIVCLVKNQQPLGATIKRHEITGDILVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSCGTIMFKVIPVSAPPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVDQNDALWWQARKISDLTICAGLIPSNHLLKRKQREFWWSQPYQPHTCLKSTRALSMEEEDSMKIDEKCVEADEETFESEELAEAKDEFVGDGQKFFIAGFRRSMRLCRRKSHFSQLHASLCCSCSCYSAVGAPYEEVVRYQRQPADKHRLIVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRFPKSYEMDGREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQDIQSARTRDLKPYVIFIKPPNTSSMRHSRKNAKITTDYYVDMKFKDEDLQEMEELAQKMESQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWVSPDTES
Tissue specificity：Detected in the retina (at protein level). Highly enriched in the retina where it is mainly expressed by rod photoreceptors; detected in the inner segment of the photoreceptor layer and in the outer nuclear layer. Also detected at much lower levels in pineal gland, cerebellum, cortex, hippocampus, olfactory bulb, heart, liver and spleen. Expressed in the CA1-CA3 regions of pyramidal cell layers and in the granule cell layer of dentate gyrus in the hippocampus. In the cerebellum, expressed in Purkinje cells and throughout the granule cell layer. In the olfactory bulb, expressed in mitral cells. {ECO:0000269|PubMed:12127943, ECO:0000269|PubMed:12384283, ECO:0000269|PubMed:12859944, ECO:0000269|PubMed:15558731}.
Induction：
Developmental stage：Expressed postnatally in the retina. The expression in the retina coincides with one of the photoreceptor specific genes. Expressed in forebrain of 9.5 dpc embryos and in whole brain of 11.5 dpc embryos. {ECO:0000269|PubMed:12127943, ECO:0000269|PubMed:12384283, ECO:0000269|PubMed:12859944}.
Protein families：MAGUK family