CCM2_MOUSE Q8K2Y9
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UniProt:Q8K2Y9
Recommended name:Cerebral cavernous malformations protein 2 homolog
EC number:
Alternative names:(Malcavernin) (Osmosensing scaffold for MEKK3)
Cleaved into:
GeneID:216527
Gene names (primary ):Ccm2
Gene names (synonym ):Osm
Gene names (ORF ):
Length:453
Mass:49917
Sequence:MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLALPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDKAKRSHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISPSQSLCAESSRGLSAGSLSESAVGPVEACCLVIMATESKVAAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDMKDSYDADASTFCFPDSGDVGGLPPLPFCMQTSPHSKTVSESELSTSATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCISLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRALSTTSTSTINGNRTTGSPDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA
Tissue specificity:Highly expressed in heart, lower expression in kidney, lung and liver (at protein level). {ECO:0000269|PubMed:14634666}.
Induction:
Developmental stage:Expressed primarily in the developing neural tube at 10.5 dpc. {ECO:0000269|PubMed:19151727}.
Protein families:CCM2 family