CCM2_MOUSE   Q8K2Y9


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UniProt:Q8K2Y9

Recommended name:Cerebral cavernous malformations protein 2 homolog

EC number:

Alternative names:(Malcavernin) (Osmosensing scaffold for MEKK3)

Cleaved into:

GeneID:216527

Gene names  (primary ):Ccm2

Gene names  (synonym ):Osm

Gene names  (ORF ):

Length:453

Mass:49917

Sequence:MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLALPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDKAKRSHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISPSQSLCAESSRGLSAGSLSESAVGPVEACCLVIMATESKVAAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDMKDSYDADASTFCFPDSGDVGGLPPLPFCMQTSPHSKTVSESELSTSATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCISLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRALSTTSTSTINGNRTTGSPDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA

Tissue specificity:Highly expressed in heart, lower expression in kidney, lung and liver (at protein level). {ECO:0000269|PubMed:14634666}.

Induction:

Developmental stage:Expressed primarily in the developing neural tube at 10.5 dpc. {ECO:0000269|PubMed:19151727}.

Protein families:CCM2 family


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