KCMF1_MOUSE Q80UY2
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UniProt:Q80UY2
Recommended name:E3 ubiquitin-protein ligase KCMF1
EC number:EC 2.3.2.27
Alternative names:(Differentially expressed in branching tubulogenesis 91) (Debt-91) (RING-type E3 ubiquitin transferase KCMF1)
Cleaved into:
GeneID:74287
Gene names (primary ):Kcmf1
Gene names (synonym ):Debt91
Gene names (ORF ):
Length:381
Mass:41791
Sequence:MSRHEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLDESSGVRHVRRMFHPGRGLGGPRARRSNMHFTSSSTGGLSSSQSSYSPSSREAMDPIAELLSQLSGVRRSAGGQLNSSGPSASQLQQLQMQLQLERQHAQAARQQLETARNASRRTNTSSVTTTITQATATANTANTENSPQALHNSQFLLTRLNDPKMSEAERQSMESERADRSLFVQELLLSTLVREESSSSDEDDRGEMADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL
Tissue specificity:Testis, liver, kidney, heart and skeletal muscle. {ECO:0000269|PubMed:12810064}.
Induction:Up-regulated during growth factor-induced branching tubulogenesis. {ECO:0000269|PubMed:12810064}.
Developmental stage:Expressed throughout embryonic development, with much higher expression after day 15, when many organs including the kidney are undergoing extensive branching morphogenesis. {ECO:0000269|PubMed:12810064}.
Protein families:KCMF1 family