ZBT7B_MOUSE Q64321
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UniProt:Q64321
Recommended name：Zinc finger and BTB domain-containing protein 7B
EC number：
Alternative names：(Krueppel-related zinc finger protein cKrox) (c-Krox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger protein 67) (Zfp-67) (Zinc finger protein Th-POK)
Cleaved into：
GeneID：22724
Gene names (primary )：Zbtb7b
Gene names (synonym )：Thpok Zfp67
Gene names (ORF )：
Length：544
Mass：58918
Sequence：MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGTVMGTGGGGTASGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATTTASTSGMPNGEDSPPQVPLLPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEAPTVLTHPLTYEEEEMVGRLGNSGGSGLGDSYSPPTGAASPAEGPLNYEVFEGEEEEEEMAYPPGYGLAQSNEPSLSPEELGSDEDPIDPDLMAYLSSLHQDALTPGLDGQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDVAAPHYPPPSTTTSSPAGLDLSNGHLDTFHLSLARFWEQSATTGPPVTTQGPPEEEEEEGTPTTPQAEGAMESS
Tissue specificity：Widely expressed, with a higher level in skin. Expressed in thymus. Restricted to CD4 cells (mature single positive CD4(+) and intermediate CD4(+)CD8(+) cells). Expressed in the luminal epithelial cells in the mammary glands where is up-regulated at late pregnancy and lactation (PubMed:29420538). Expression is enriched in brown fat (PubMed:28784777). {ECO:0000269|PubMed:15729333, ECO:0000269|PubMed:28784777, ECO:0000269|PubMed:29420538, ECO:0000269|PubMed:7937772}.
Induction：Expression in mammary glands is induced by insulin. {ECO:0000269|PubMed:29420538}.
Developmental stage：Expressed, beginning at 9.5 days of gestation and at 10.5 days in regions destined to become skin. In adult animals, expression is predominantly in skin (PubMed:7937772). Expression is significantly increased during brown adipocyte differentiation (PubMed:28784777). {ECO:0000269|PubMed:28784777, ECO:0000269|PubMed:7937772}.
Protein families：