GLIS2_MOUSE Q8VDL9
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UniProt:Q8VDL9
Recommended name:Zinc finger protein GLIS2
EC number:
Alternative names:(GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5)
Cleaved into:
GeneID:83396
Gene names (primary ):Glis2
Gene names (synonym ):Gli5 Nkl
Gene names (ORF ):
Length:521
Mass:55842
Sequence:MHSLDEPLDLKLSITKLRAAREKRERTLGVVRHHALHRELGLVDDSPAPGSPGSPPPGFLLNPKFPEKVDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPECQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLPPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLPPGPLDLSALACGNGGGGGGGIGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTPLERTERSRSRPSPDGLPLLPGTVLDLSTGNSAASSPEVLTPGWVVIPPGSVLLKPAVVN
Tissue specificity:Expressed at high levels in kidney, and at lower levels in heart and lung. {ECO:0000269|PubMed:11741991}.
Induction:
Developmental stage:Expression begins at 9.5 dpc in cranial ganglia, dorsal root ganglia and neural tube. At 10.5 dpc, broadly expressed in the intermediate zone of the hindbrain, spinal cord and dorsal root ganglia. By 12.5 dpc, expression in the spinal cord becomes restricted to a narrow band of cells in the ventricular zone. {ECO:0000269|PubMed:11262234}.
Protein families:GLI C2H2-type zinc-finger protein family