GLIS2_MOUSE   Q8VDL9


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UniProt:Q8VDL9

Recommended name:Zinc finger protein GLIS2

EC number:

Alternative names:(GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5)

Cleaved into:

GeneID:83396

Gene names  (primary ):Glis2

Gene names  (synonym ):Gli5 Nkl

Gene names  (ORF ):

Length:521

Mass:55842

Sequence:MHSLDEPLDLKLSITKLRAAREKRERTLGVVRHHALHRELGLVDDSPAPGSPGSPPPGFLLNPKFPEKVDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPECQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLPPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLPPGPLDLSALACGNGGGGGGGIGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTPLERTERSRSRPSPDGLPLLPGTVLDLSTGNSAASSPEVLTPGWVVIPPGSVLLKPAVVN

Tissue specificity:Expressed at high levels in kidney, and at lower levels in heart and lung. {ECO:0000269|PubMed:11741991}.

Induction:

Developmental stage:Expression begins at 9.5 dpc in cranial ganglia, dorsal root ganglia and neural tube. At 10.5 dpc, broadly expressed in the intermediate zone of the hindbrain, spinal cord and dorsal root ganglia. By 12.5 dpc, expression in the spinal cord becomes restricted to a narrow band of cells in the ventricular zone. {ECO:0000269|PubMed:11262234}.

Protein families:GLI C2H2-type zinc-finger protein family


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