FIGN_MOUSE Q9ERZ6
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UniProt:Q9ERZ6
Recommended name：Fidgetin
EC number：
Alternative names：
Cleaved into：
GeneID：60344
Gene names (primary )：Fign
Gene names (synonym )：
Gene names (ORF )：
Length：759
Mass：82098
Sequence：MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQATPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNNSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWIGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLTQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
Tissue specificity：Widely expressed. {ECO:0000269|PubMed:11017077}.
Induction：
Developmental stage：Expression begins in the embryo at 8.5 dpc. Oocyst, optic cup and pelvic anlage show strongest expression. At 10.5 dpc, expression concentrated in epithelial cells of the dorso-lateral, posterior and anterior otocyst wall. Expression in the eye is found fairly evenly throughout the retinal neural epithelium, with some enrichment in the inner retina where cells begin their differentiation to form retinal ganglion cells. Some expression is seen in the lens pit and in the cell layer that will become the pigment epithelium. At 11.5 dpc, when the superior semicircular canal has begun to form from the posterior otocyst, much of the expression is concentrated there, although there is also expression in the part of the otocyst that will form the lateral or horizontal canal. Strong expression was also seen in the acoustic ganglia and cochlea. In the eye the expression pattern is similar to that found in 10.5 dpc except that expression is concentrated in the retinal ganglion layer. As the lens vesicle forms and matures at 13 dpc, expression is also seen in the anterior wall of the lens, but persists throughout the neural retina, especially in the peripheral retina where cells are still differentiating. {ECO:0000269|PubMed:11017077}.
Protein families：AAA ATPase family