3BHS4_MOUSE Q61767
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UniProt:Q61767
Recommended name:NADPH-dependent 3-keto-steroid reductase Hsd3b4
EC number:EC 1.1.1.270
Alternative names:(3 beta-hydroxysteroid dehydrogenase type 4) (3 beta-hydroxysteroid dehydrogenase type IV) (3 beta-HSD IV) (Dihydrotestosterone 3-ketoreductase) (EC 1.1.1.210)
Cleaved into:
GeneID:100043456
Gene names (primary ):Hsd3b4
Gene names (synonym ):
Gene names (ORF ):
Length:373
Mass:41766
Sequence:MPGWSCLVTGAGGFLGQRIVRMLVQEEELQEIRALFRTFGRKQEEELSKLQTKTKVTVLKGDILDAQCLKRACQGMSAVIHTAAAIDPLGAASRQTILDVNLKGTQLLLDACVEANVPTFIYSSSVLVAGPNSYKEIILNAHEEEHHESTWSNPYPYSKKMAEKAVLAANGSILKNGGTLHTCALRLSFIYGEECQVTSTTVKTALKNNSIIKKNATFSIANPVYVGNAAWAHILAARSLQDPKKSPSIQGQFYYITDDTPHQSYDDLKCTLSKEWGLRLDTSWSLPLPLLYWLAFLLETVSFLLRPVYNYRPPFNRLLITVLNSVFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVMQHREIGNKKSQ
Tissue specificity:Kidney (at protein level); found only in the cortex, appears to be associated with the proximal tubules; and a minor expression in testis. {ECO:0000269|PubMed:8145763}.
Induction:
Developmental stage:Expression between 15-20 days post-implantation occurs only in the kidney of the male fetus and not in the female, whereas a similar expression is found in adult male and female kidneys. {ECO:0000269|PubMed:8145763}.
Protein families:3-beta-HSD family