NPAS3_MOUSE Q9QZQ0
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UniProt:Q9QZQ0
Recommended name:Neuronal PAS domain-containing protein 3
EC number:
Alternative names:(Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)
Cleaved into:
GeneID:
Gene names (primary ):Npas3
Gene names (synonym ):Mop6
Gene names (ORF ):
Length:925
Mass:100458
Sequence:MGRAGAAANGTPQNVQGITSYQQRITAQHPLPNQSECRKIYRYDGIYCESTYQNLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTISYLKMRDFANQGDPPWNLRMEGPPPNTSVKGAQRRRSPSALAIEVFEAHLGSHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGDHVEMAEQLGMKLPPGRGLLSQGTTEDAASSASSSSQSETPEPVETTSPSLLTTDNTLERSFFIRMKSTLTKRGVHIKSSGYKVIHITGRLRLRVPLSHGRTVPSQIMGLVVVAHALPPPTINEVRIDCHMFVTRVNMDLNIIYCENRISDYMDLTPVDIVGKRCYHFIHAEDVEGIRHSHLDLLNKGQCVTKYYRWMQKNGGYIWIQSSATIAINAKNANEKNIIWVNYLLSNPEYKDTPMDIAQLPHLPEKASESSETSDSESDSKDTSGITEDNENSKSDEKGNQSENSEDPEPDRKKSGSACDNDMNCNDDGHSSSNPDSRDSDDSFEHSDFEHPKAAEDGFGALGPMQIKVERYVESEADLRLQPCESLTSDSAKDSDSANEAGAQASSKHQKRKRRRKRQKGGSASRRRLSSASSPGLDAGLVEPPRLLSSPHSASVLKIKTEIAEPINFDNESSIWNYPPNREISRNESPYSMTKPPTSEHFPSPQGQGGSIGGGGALHVAIPDSVLTPPGADGTAGRKTQFSGTAPVPSDPLSPPLSASPRDKHPGGGAGSGGGGPGASNSLLYTGDLEALQRLQAGNVVLPLVHRVTGTLAATSTAAQRVYTTGTIRYAPAEVTLAMQGNLLPNAHAVNFVDVNSPGFGLDPKTPMEMLYHHVHRLNMSGPFGGAVSAASLTQMPGGNVFTTAEGLFSTLPFPVYSNGIHAAQTLERKED
Tissue specificity:Detected exclusively in adult brain in inhibitory interneurons.
Induction:
Developmental stage:Expression detected between 9.5 and 11.5 dpc in the developing neural tube. Was also expressed throughout the neuroepithelium of the developing central nervous system between 10. 5 and 12.5 dpc at 14.5 dpc, the expression became restricted to the neopallial layer of the cortex. At 12.5 dpc, expression was evident in nonneural tissues such as the developing dermis and mesenchyme surrounding the otic and nasal placodes. Expression was also detected in the developing cardiac valves, limb and developing kidney.
Protein families: