TNK1_MOUSE Q99ML2
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UniProt:Q99ML2
Recommended name：Non-receptor tyrosine-protein kinase TNK1
EC number：EC 2.7.10.2
Alternative names：(Kinase of embryonic stem cells)
Cleaved into：
GeneID：83813
Gene names (primary )：Tnk1
Gene names (synonym )：Kos1
Gene names (ORF )：
Length：666
Mass：73099
Sequence：MLPEASSLWLLRLLRDVQLAQFYRPILEELNVTRPEHFDFVRPEDLDNIGMGRPAQRRLNEALKRYRSGVKSKNWVYKILGGFAPEQKEIPPRSDSPLCFHEPEGGLKCLIPEGAVRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQEAWLSEGRCVREVTEPGALRMEPGDPITIIEGSLDTATWKGQNGRTLKVGNFPASAVTLADLGGSPVTHPAHRGSPAHGEKCRGGTDGDREKATLQDLPPARSHRTKMPLQRMRGISKSLESVLSLGPRPTGGGSSPPELRRTRAMPQRLPDLPPRPPDLPPRPPIICNSSQPTQPHKARPKRESSHNHRTGAPGASKATVPSGGPLSDPEWQRKVVEVELSVHGVTYQECQVALRTTGGDVASAIRNLKVDQLFHLSNRSRADCRRILEHHQWDLSAASRYILARS
Tissue specificity：Expressed in whole embryo and all adult tissues examined including liver, kidney, heart, brain, skeletal muscle and intestine. Also detected in various myeloid- and lymphoid-derived cell lines. {ECO:0000269|PubMed:12789265}.
Induction：
Developmental stage：Expression during embryogenesis increases between 7 dpc and 11 dpc. Levels of expression subsequently decrease and reach a steady-state level by 17 dpc. {ECO:0000269|PubMed:12789265}.
Protein families：Protein kinase superfamily, Tyr protein kinase family