SATB2_MOUSE Q8VI24
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8VI24
Recommended name：DNA-binding protein SATB2
EC number：
Alternative names：(Special AT-rich sequence-binding protein 2)
Cleaved into：
GeneID：212712
Gene names (primary )：Satb2
Gene names (synonym )：Kiaa1034
Gene names (ORF )：
Length：733
Mass：82559
Sequence：MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGANVNITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPTKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAETDQR
Tissue specificity：Expressed in cortical neurons that extend axons across the corpus callosum. Also expressed in branchial arches and in cells of the osteoblast lineage, but not in chondrocytes and osteoclasts. {ECO:0000269|PubMed:16751105, ECO:0000269|PubMed:18255030}.
Induction：
Developmental stage：Expression first detected at 10.5 dpc in the maxillary component of the first pharyngeal arch and the lateral aspect of the frontonasal process in the regions that will subsequently fuse to form the primary palate. At 11 - 11.5 dpc, the expression pattern demarcates the region of the medial aspect of the maxillary process within the primitive oral cavity, which will form the palate shelf. By 12.5 dpc, symmetrical expression is seen in the medial edges of the developing palate shelves and this continues until 13.5 dpc when the strongest expression is in the mesenchyme underlying the medial edge epithelia. By the time of palatal shelf fusion at 14.5 dpc the expression is dramatically down-regulated. No expression detected elsewhere in the embryo at any stage examined. {ECO:0000269|PubMed:12915443}.
Protein families：CUT homeobox family