PCDP1_MOUSE A9Q751
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UniProt:A9Q751
Recommended name:Cilia- and flagella-associated protein 221
EC number:
Alternative names:(Primary ciliary dyskinesia protein 1)
Cleaved into:
GeneID:226356
Gene names (primary ):Cfap221
Gene names (synonym ):Gm101 Pcdp1
Gene names (ORF ):
Length:836
Mass:96956
Sequence:MEVVKSPMQELQQAKEPFDTMSPLLLKSLVEEPKKRTEVPNHLLESRVYAKLLNNKVIQARPGIVHFGGYEIESKHQQILNIANISDEDTHLHILPPQTKYFQINFEKKEHRLIPGLSLTVTITFSPDEWRYYYDCIRIHCKGDDTLLVPIHAYPVLNNLDFPTFINLSDVFLGESKSYVIPLQCSCPVDFEFHITLLRSHQAFTIEPKSGIIPANGKAKVTVKFTPIQYGMAQIKIQLWISQFNSQPYECVFTGTCYPNMALPLEEFKRLNTRSKKVNVPLEKTTYVQFYPAPAKAKPQKLKEIDYQDLRFPADLSNPFAVATVLNQEPGKLKIKELKQVLDQGDEISKTRQMKEAIFEQKVRQDILTEIENHLKWQVHLGKEHTTYRFKRELTEEWKKARAKYKQNRGDPVEGEELQRLQTEQSQKRIVRDLKGKRQEFHPNFDPLVNNVWLTRHRAQRRFQQAARKIMLERRLLSMLGAIRGMDKESILRKIIQVNGKLIQGENPSRGRRAHLKQEDNIWRYSLESEEVLHFAFPTDSESYNELALDGLGLVPIKSPEIQIKHSYPYFTLKVPQLYKIKGYHPFSVNKSSTNYRLQKLARPLKHGAEDEVTTIITIPKKDTTPLSAKPSILSMKPPEGLAMSVEYDPLYIFNPSPGLFAVKHPLTYAETLIDYHLCSHPKYKYTQESHMGSSIPLTQRQFLHHTDIIPGIMNWKKFQPLVFSSMSDPSMVEATQRSDWYSSVMLPIDVPAPLEDLPEEDRLETTERDLCDQGIEVMLTPEMVQVEFPMLIHRDSKKEKDFKDSTQLPEKVGERVQEEMKNLRSKALNTYLILD
Tissue specificity:Expressed in testis, specifically in developing spermatocytes and spermatids but not in immature spermatogonia. Expressed in the ciliated respiratory epithelial cells lining the sinuses, trachea and bronchi (at protein level). {ECO:0000269|PubMed:15613475, ECO:0000269|PubMed:18039845}.
Induction:
Developmental stage:Expression in testis starts at P20. {ECO:0000269|PubMed:15613475}.
Protein families:PCDP1 family