OXLA_MOUSE O09046
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UniProt:O09046
Recommended name：L-amino-acid oxidase
EC number：EC 1.4.3.2
Alternative names：(LAAO) (LAO) (Interleukin-4-induced protein 1) (IL4-induced protein 1) (mIL4I1) (Protein Fig-1) (mFIG1)
Cleaved into：
GeneID：100328588
Gene names (primary )：Il4i1
Gene names (synonym )：Fig1
Gene names (ORF )：
Length：630
Mass：70191
Sequence：MAGLALRLVLAATLLGLAGSLDWKAASSLNPIEKCMEDHDYEQLLKVVTLGLNRTSKPQKVVVVGAGVAGLVAAKMLSDAGHKVTILEADNRIGGRIFTFRDEKTGWIGELGAMRMPSSHRILHKLCRTLGLNLTQFTQYDENTWTEVHNVKLRNYVVEKMPEKLGYNLNNRERGHSPEDIYQMALNKAFKDLKALGCKKAMNKFNKHTLLEYLLEEGNLSRPAVQLLGDVMSEEGFFYLSFAEALRAHACLSDRLRYSRIVGGWDLLPRALLSSLSGALLLNAPVVSITQGRNDVRVHIATSLHSEKTLTADVVLLTASGPALQRITFSPPLTRKRQEALRALHYVAASKVFLSFRRPFWHEEHIEGGHSNTDRPSRLIFYPARGEGSLLLASYTWSDAAAPFAGLSTDQTLRLVLQDVAALHGPVVFRLWDGRGVVKRWAEDPHSQGGFVVQPPLYGREAEDYDWSAPFGRIYFAGEHTALPHGWVETAVKSGLRAAVRINNNYGYGEVDPQMMEHAYAEANYLDQYPEGERPEEQQAREEVSPDEQEPSHKHLLVETSPEGQQHAFVEAIPELQGHVFVETVPQEKGHAHQNIYPSEHVQVHGEVIPEWHGHGGSGTPQMHRVGDHS
Tissue specificity：Primarily found in immune tissues. {ECO:0000269|PubMed:16029492, ECO:0000269|PubMed:9122225}.; [Isoform 1]: Primarily found in immune tissues, mostly in B-lymphocytes. {ECO:0000269|PubMed:16029492}.; [Isoform 2]: Restricted to the testis, predominantly in Sertoli cells at the periphery of the ducts, and the brain, including Purkinje cells, hippocampus and mitral cells in the olfactory bulb. No isoform 2 expression in fetal tissues. {ECO:0000269|PubMed:16029492}.
Induction：By interleukin-4. {ECO:0000269|PubMed:9122225}.
Developmental stage：Expression increases during bone marrow-derived macrophage (BMDM) differentiation: expression is much higher in primary macrophages than monocytes. {ECO:0000269|PubMed:26599209}.
Protein families：Flavin monoamine oxidase family, FIG1 subfamily